S.E.M.I. – Side Effects May Include...
S.E.M.I. is a single-player and co-op action platformer with puzzle elements. Play as patients of an unusual clinic, take experimental drugs, interfere with each other, and be ready for chaos and unpredictable side effects!
Offers
What are keyshops?Keyshops
Third-party resellers. Often cheaper, without official store support. Keyshop prices vs Steam →
Multipacks (1)
DLCs (3)
About S.E.M.I. – Side Effects May Include...
S.E.M.I. is a cooperative online game about escaping from a special clinic. Here, you and up to 3 of your brainless loyal friends play as patients, fighting staff and other patients while stumbling into all sorts of unexpected situations. Brawls, side-effect pills, and brutal platforming will absolutely challenge your clumsy friends’ hands sense of teamwork. Expect obstacles, puzzles, deadly traps, and rooms where a single wrong move can knock out the entire squad.
Communicate in voice chat and arrange sabotage help your friends pass through rooms, get out of traps and fight with opponents! In your arsenal: close combat, physics, amazing abilities and ... imagination!
Take pills and get abilities:
Bipolar force is an invulnerable monster, then a helpless rag!
Laser astigmatism — two sights, one laser… Where will he shoot?
Stendhal syndrome — are you looking at a painting? Now you're hysterical and destroying everything around you!
Alice's syndrome is either tiny or gigantic — have time to adjust!
Madness is near! You and your friends can go crazy and start running, jumping and fighting, and your abilities will become uncontrollable. Do you want to take back control? Take the pills :)
Locations are randomly generated from rooms with changing gravity, traps, moving walls, and other "pleasant" surprises.
After a successful escape, you will receive a medical report: "The patient was stable until he started hitting the guards with a bottle. Diagnosis: Overmotivation" or something worse!
Unlock new costumes and decorations. Let each new escape be more stylish than the previous one!
Will you and your friends be able to escape... or at least not go crazy?
Welcome to the mental hospital! Here, your abilities are a lottery, and your friends can be the most dangerous opponents!
Game details
Game details
Age ratings
Languages
Features
S.E.M.I. – Side Effects May Include... price history
Lowest tracked price: £3.59 (Jul 18, 2026) · current best: £3.88 across 2 stores.
S.E.M.I. – Side Effects May Include... player count & reviews
86% positive reviews all-time · 5 peak players in the last 30 days.
S.E.M.I. – Side Effects May Include... — frequently asked questions
Where can I buy S.E.M.I. – Side Effects May Include... at the cheapest price?
Right now the cheapest offer for S.E.M.I. – Side Effects May Include... is £3.88 at K4G. KingsPrice compares 2 offers from 2 stores — official stores and keyshops — and refreshes prices throughout the day.
What is the lowest price S.E.M.I. – Side Effects May Include... has ever been?
The lowest price KingsPrice has tracked for S.E.M.I. – Side Effects May Include... is £3.59 (recorded on Jul 18, 2026). This covers the stores and period we monitor — set a price alert to catch the next drop to that level.
How many people play S.E.M.I. – Side Effects May Include...?
S.E.M.I. – Side Effects May Include... peaked at 5 concurrent players on Steam in the last 30 days (highest on Jul 9, 2026). The player chart on this page updates daily.
Is it safe to buy a S.E.M.I. – Side Effects May Include... Steam key from a keyshop?
Keyshops are marketplaces that resell game keys, usually below official store prices. The keyshops listed on KingsPrice deliver genuine Steam keys, but buyer protection differs from official stores — check the shop's rating and refund policy before buying. You can hide keyshop offers at any time with the keyshops toggle. Keyshop prices vs Steam →
How can I get S.E.M.I. – Side Effects May Include... at a discount?
Create a free price alert on this page and KingsPrice will email you when S.E.M.I. – Side Effects May Include... drops below your chosen price. The biggest discounts usually appear during seasonal Steam sales and publisher promotions — the sale calendar on this page shows the next confirmed event.
System requirements
Minimum
- Requires a 64-bit processor and operating system
- OS: Windows 10
- Processor: Intel Core i5 series or Ryzen series
- Memory: 8 GB RAM
- Graphics: GTX 960 or AMD R9 290
- DirectX: Version 11
- Storage: 3 GB available space
Recommended
- Requires a 64-bit processor and operating system
- OS: Windows 11
- Processor: Intel Core i7 series or Ryzen series
- Memory: 8 GB RAM
- Graphics: GTX 1660 or RX6600
- DirectX: Version 12
- Storage: 3 GB available space
