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A twisted trial of pill roulette for up to 4 players (solo or online). Pick your poison. Use experimental items to shift the odds. And remember: only one of you can survive.
Price history tracked since Jul 7, 2026 · vs all tracked offers.
Based solely on tracked price history — not purchase advice.
Tracked since Jul 7, 2026.
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Welcome to Side Effects: a tense, turn-based medical roulette game. Each round you'll be presented with a selection of pills. Some are helpful, some are harmful, and some mean instant death. You never know what you're about to consume or what it might do to your mind or body. Winning means outlasting – AKA, outliving – your opponent across the table.
Every pill impacts your resistance. Manage it wisely: zero resistance means death.
Between rounds, you can choose from a range of experimental items and treatments that can shift the odds in your favor, from vaccines to mouth clamps.
The other patient wants to outlast you. They’ll bluff, adapt, and use everything at their disposal to keep breathing one dose longer than you.
Would you like to participate?
A single player mode
A multiplayer mode (2-4 Players)
15+ unique items
6 pill types to test
